MICROCALORIMETRY
Microcalorimetry uses a suite of techniques to directly measure enthalpy and heat capacity changes that arise when chemical reactions occur. In aqueous solutions, heat flux into or out of the sample almost always happens on reaction. These reactions may involve a wide variety of situations, e.g., the interaction of two molecules (such as a cyclodextrin and its guest), changes in the conformation of complex macromolecules (such as proteins or DNA), or even in the structure of very complex multimolecular colloidal drug delivery systems (such as liposomes).
