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The World of Microorganisms

The number and diversity of microorganisms infecting humans and animals is ever increasing. Understanding how microbes cause disease and evade treatment is crucial for the protection of global public health. Bruker supports researchers and healthcare providers in the rapid identification and analysis of microorganisms. Our intuitive, robust instrumentation and software solutions meet the needs of both clinical microbiologists and those in industrial and applied microbiology.

  •  Clinical Diagnostic

Species level identification of microorganisms is vital in combating the vast range of pathogens that infect humans. Bacteria, yeast and mycobacteria, whether clinically common or rare, can cause serious harm when not identified and treated quickly. Increasingly prevalent conditions, such as sepsis or multi-drug resistant (MDR) microorganism infections, pose a serious threat to hospitals and wider public health, requiring rapid, automated microbial identification and resistance testing solutions for the entire clinical workflow.

In parallel, effective hygiene management – especially in hospitals – is key to prevent healthcare associated infections as effectively as possible.

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  • Food & Beverage Microbiology

Accurate microbiological testing technology is vital for the detection of foodborne pathogens, possible food spoilage organisms and technological strains. Rapid identification/confirmation and strain typing methods enable food and beverage manufacturers to make fast quality and safety decisions.

MALDI Biotyper® and IR Biotyper® - A seamless solution for microorganism confirmation/identification and strain typing in food microbiology

Only one well-equipped benchtop furnished with the dedicated MALDI Biotyper® solution for food microbiology, complemented by the IR Biotyper®, is needed for confirmation/identification and strain typing of microorganisms in less than 3 hours.

·         The MALDI Biotyper® provides specific and reliable identification of microorganisms within minutes. The system has been validated and certified according to the Official Method of Analysis program (OMA) of the AOAC International and according to the new ISO 16140-part 6 standard.

·        The IR Biotyper® allows for easy, fast and cost-effective microbial typing for real-time quality control and source tracking.

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  • Pharmaceutical Microbiology

Pharmaceutical microbiologists are responsible for ensuring that the supply of life-saving drugs and vaccines are free from microorganism contamination. By maintaining product safety and quality with reliable microbial testing, the downtime of production and delay in deliveries can be minimized, while ensuring regulatory compliance. Pharmaceutical companies require microbial identification not only for production line control, but also for sterile products such as vaccines.

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  • Water Testing Microbiology

Many water testing laboratories still rely on traditional techniques, such as most probable number (MPN), light microscopy or biochemical techniques, to test for microbes in water systems. Ensuring the quality and safety of drinking, industrial and natural water requires a rapid, robust technology to isolate and identify potentially pathogenic microorganisms like Legionella to minimize risk to public health.

Legionella represents a significant concern for water microbiologists. At least 61 different species have been described, many of which cause legionellosis in humans. The opportunistic waterborne pathogen Legionella pneumophila poses a particular risk, as it is widespread in natural water sources and can lead to Legionnaires disease. Other microorganisms, such as coliforms, E. coli, Pseudomonas aeruginosa, Salmonella spp., Enterococcus spp., sulfite-reducing anaerobes (Clostridium), and other environmental contaminants, are also important pathogens that require rigorous testing.

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  • Microbiological Research

Understanding the epidemiology of various microorganisms is a key focus of microbiological research laboratories across the globe. Accurate and rapid microbial identification is vital for tracking the pathogenicity, virulence and antimicrobial resistance of strains and subspecies in the population, for clinical researchers as well as those in the food, veterinary, environmental and pharmaceutical industries.

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  • Veterinary Microbiology

Among the current critical challenges faced by veterinary microbiologists is the need to obtain secure species identification of rare and challenging organisms affecting animals, in a timely manner. These microorganisms can be pathogenic to animals, or can be asymptomatic to the animal vector but cause disease in humans, usually via a foodborne route. Control of zoonoses is also implicated in food microbiology, for example for Salmonella and Campylobacter surveillance in the production of eggs and whole milk.

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